/ Nov 05, 2025
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Kale and Tea Compound Found to Be Most Effective at Reducing Inflammation

Study Identifies Flavonoids That Enhance Immune Regulation

Kaempferol, a flavonoid found in kale, tea, spinach, and broccoli, significantly reduces inflammation by promoting immune regulation, according to research published in Allergy. The study screened over 40 flavonoids and identified kaempferol as the most effective in enhancing immune tolerance. Quercetin, found in apples and onions, and fisetin, present in strawberries, were also effective but less potent. These findings highlight the critical role of dietary choices in managing inflammation.

The study revealed that kaempferol increases the function of specific immune cells responsible for reducing inflammation, making it a key compound in anti-inflammatory diets. Patients with inflammatory or autoimmune conditions may experience better immune regulation by including foods rich in kaempferol. In addition, quercetin and fisetin offer complementary benefits and are readily accessible in everyday diets, providing multiple options for achieving immune balance.

Researchers emphasized that diets abundant in flavonoid-rich foods could be a cornerstone of natural therapies for chronic inflammatory conditions. For patients with autoimmune diseases, allergies, or other inflammation-driven disorders, foods like leafy greens, cruciferous vegetables, onions, apples, and berries represent practical, impactful dietary tools to reduce inflammatory responses.

Reference

Takahashi M, Nagata K, Watanuki Y, et al. Kaempferol Exerts Anti-Inflammatory Effects by Accelerating Treg Development via Aryl Hydrocarbon Receptor-Mediated and PU.1/IRF4-Dependent Transactivation of the Aldh1a2/Raldh2 Gene in Dendritic Cells. Allergy. Published December 11, 2024.

Study Identifies Flavonoids That Enhance Immune Regulation

Kaempferol, a flavonoid found in kale, tea, spinach, and broccoli, significantly reduces inflammation by promoting immune regulation, according to research published in Allergy. The study screened over 40 flavonoids and identified kaempferol as the most effective in enhancing immune tolerance. Quercetin, found in apples and onions, and fisetin, present in strawberries, were also effective but less potent. These findings highlight the critical role of dietary choices in managing inflammation.

The study revealed that kaempferol increases the function of specific immune cells responsible for reducing inflammation, making it a key compound in anti-inflammatory diets. Patients with inflammatory or autoimmune conditions may experience better immune regulation by including foods rich in kaempferol. In addition, quercetin and fisetin offer complementary benefits and are readily accessible in everyday diets, providing multiple options for achieving immune balance.

Researchers emphasized that diets abundant in flavonoid-rich foods could be a cornerstone of natural therapies for chronic inflammatory conditions. For patients with autoimmune diseases, allergies, or other inflammation-driven disorders, foods like leafy greens, cruciferous vegetables, onions, apples, and berries represent practical, impactful dietary tools to reduce inflammatory responses.

Reference

Takahashi M, Nagata K, Watanuki Y, et al. Kaempferol Exerts Anti-Inflammatory Effects by Accelerating Treg Development via Aryl Hydrocarbon Receptor-Mediated and PU.1/IRF4-Dependent Transactivation of the Aldh1a2/Raldh2 Gene in Dendritic Cells. Allergy. Published December 11, 2024.

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It is a long established fact that a reader will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more-or-less normal distribution of letters, as opposed to using ‘Content here, content here’, making it look like readable English. Many desktop publishing packages and web page editors now use Lorem Ipsum as their default model text, and a search for ‘lorem ipsum’ will uncover many web sites still in their infancy.

The point of using Lorem Ipsum is that it has a more-or-less normal distribution of letters, as opposed to using ‘Content here, content here’, making

The point of using Lorem Ipsum is that it has a more-or-less normal distribution of letters, as opposed to using ‘Content here, content here’, making it look like readable English. Many desktop publishing packages and web page editors now use Lorem Ipsum as their default model text, and a search for ‘lorem ipsum’ will uncover many web sites still in their infancy.

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It is a long established fact that a reader will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more-or-less normal distribution

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